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Dipeptidase 1
・ Dipeptidase 2
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・ Dipeptide hydrolase
・ Dipeptidyl aminopeptidase III
・ Dipeptidyl carboxypeptidase
・ Dipeptidyl peptidase
・ Dipeptidyl peptidase-4
・ Dipeptidyl peptidase-4 inhibitor
・ Dipeptidyl-dipeptidase
・ Dipeptidyl-peptidase I
・ Dipeptidyl-peptidase II


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Dipeptidase 1 : ウィキペディア英語版
Dipeptidase 1

Dipeptidase 1 is an enzyme that in humans is encoded by the ''DPEP1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1800 )
== Function ==

DPEP1 (EC 3.4.13.11) is a kidney membrane enzyme that hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates, e.g., leukotriene D4 (Kozak and Tate, 1982). DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem (Campbell et al., 1984). Earlier, beta-lactamase enzymes were thought to occur only in bacteria, where their probable function was in protecting the organisms against the action of beta-lactam antibiotics. These antibiotics exhibit selective toxicity against bacteria but virtual inertness against many eukaryotic cells (Adachi et al., 1990).(by OMIM )〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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